Mary Sweeney is an American director, writer, film editor and film producer. She was briefly married to American film director David Lynch, with whom she collaborated for 20 years. Sweeney worked with Lynch on several films and television series, most notably the original Twin Peaks series (1990), Lost Highway (1997), The Straight Story (1999), and Mulholland Drive (2001). Sweeney is the Dino and Martha De Laurentiis Endowed Professor in the Writing Division of the School of Cinematic Arts at the University of Southern California. She was formerly the chair of the Film Independent board of directors.

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